Found 8 matching trials
Combination Study of Guadecitabine/ASTX727 and Pembrolizumab
PHASE1HyPeR is a multi-centre Phase 1 Dose Escalation Study of Guadecitabine (SGI...
Status
Active Not Recruiting
Location
Royal Marsden Hospital
Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer
PHASE1This is a phase I/II study of the combination of Guadecitabine (SGI-110) an...
Location
USC / Norris Comprehensive Cancer Center
A Study Investigating SGI-110 in Combination With Ipilimumab in Unresectable or Metastatic Melanoma Patients
PHASE1Thi pahse I, dose-escalation trial will determine the MTD, safety and the a...
Location
Medical Oncology and Immunotherapy Unit, University Hospital of Siena
Decitabine and Talazoparib in Untreated AML and R/R AML
PHASE1The purpose of this study is to find the best way to combine a new chemothe...
Location
University of Maryland Greenebaum Comprehensive Cancer Center
SGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)
PHASE1Phase 1-2 dose-escalation randomized study in participants with intermediat...
Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer
PHASE1This phase Ib/II trial studies the side effects and best dose of guadecitab...
Location
USC / Norris Comprehensive Cancer Center
SGI-110 Plus Durvalumab/Tremelimumab in SCLC
PHASE1The purpose of this study is to determine if a combination of investigation...
Location
Columbia University Medical Center
SGI-110 in Combination With Carboplatin in Ovarian Cancer
PHASE2A 2-part, Phase 2 controlled, open-label, randomized study in participants ...
Location
Norris Comprehensive Cancer Center- University of Southern California